This slideshow is a supplement to the Sleep-Wake Neuroanatomy review available in this chapter. Key structures: hypothalamus, ventrolateral and median preoptic hypothalamus, lateral hypothalamus, orexin, pedunculopontine nucleus, lateral dorsal tegmental nucleus, locus coeruleus, raphe nucleus, substantia nigra, ventral tegmental area, basal forebrain, tuberomammillary nucleus, sublaterodorsal nucleus, peri-locus coeruleus, ventrolateral periaqueductal gray, suprachiasmatic nucleus, paraventricular nucleus, superior cervical ganglion, spinal cord, pineal gland, melatonin.